SEMA
30mg · 3ml
SKU: SM-30mg
Semaglutide is a synthetic GLP-1 receptor agonist that mimics the naturally occurring gut hormone glucagon-like peptide-1 to regulate appetite and metabolism. It strengthens satiety signals, slows gastric emptying, improves insulin secretion, and modulates gut-brain communication to support weight loss and glycemic control.
Available Options
Product Specifications
Strength
30mg
Volume / Qty
3ml
Form
Lyophilized Powder
Suggested Retail Price
$386.00
Dosing Guide
Recommended Dose
Per clinician protocol
Route
Subcutaneous
Frequency
Once weekly
Clinician Access Required
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SEMA is available exclusively to verified clinicians under IRB-approved research protocol PPRN-001-2025.
IRB-Approved Research Protocol
PPRN-001-2025 ·IRCM-2025-467
Approved December 3, 2025 · Principal Investigator: Dr. M. Scott Mortensen, MD, MPAS, MLT
Save up to 80% with the 5,000 Foundation Bundle
SEMA is included in this clinic-tier package. Bundle includes weight loss (tirz & reta) + longevity/repair (mots-c, ghk-cu, bpc-157, epithalon) with 1 free Tirz 15mg as a bonus.
For Clinicians
Clinical Reference
Pharmacology, safety, monitoring, and dosing reference for SEMA. Always individualize based on patient context.
Mechanism of Action
Receptor / Target
GLP-1 receptor agonist
Half-Life
~7 days (weekly dosing)
Onset of Action
Appetite suppression within days; weight loss 4–12 weeks
Metabolism
Proteolytic cleavage; minimal renal clearance
Cautions & Contraindications
Contraindicated In
- Personal or family history of medullary thyroid carcinoma
- MEN-2 syndrome
- Pregnancy and lactation
- Hypersensitivity to semaglutide
Use Caution With
- Pancreatitis history
- Severe gastroparesis or chronic GI motility disorders
- Diabetic retinopathy
- Suicidal ideation history
- Gallbladder disease
Suggested Labs to Monitor
HbA1c
Baseline / 12 weeksFasting glucose, fasting insulin
Baseline / 12 weeksLipase and amylase
Baseline / as symptoms warrantLipid panel
Baseline / 12 weeksLab interpretation guidance comes from peer-reviewed literature. Always individualize based on patient context.
Reconstitution Calculator
Calculate exactly how many units to draw on a U-100 insulin syringe for your target dose. Pre-filled with SEMA defaults — adjust as needed.
Total peptide in the vial (e.g. 10mg)
Volume of BAC water used to reconstitute
Single-injection dose in micrograms
Draw to
Per mL
10000 mcg
Doses per vial
~120
Always double-check reconstitution math. This tool is for reference — clinician supervision required.
Plumb DISCOVER
What SEMA targets
Patient goals, biomarkers, and wearable signals this peptide addresses. Powers the future Plumb AI protocol engine.
Patient Goals
Biomarkers Tracked
Wearable Signals
Essential Protocol Packages
SEMA is part of 1 clinical protocol
Bundle this peptide with synergistic compounds at clinic-tier pricing.
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